Vascular dysfunction is an early feature of diabetic vascular disease, due to increased oxidative stress and reduced nitric oxide (NO) bioavailability.This can lead to endothelial cell senescence and clinical complications such as stroke.Cells can become senescent by shortened telomeres and oxidative stress is known to accelerate telomere attrition
Background.Of particular importance in the repair process for cephalohematomas is the pathological remodeling of the bones of the cranial vault.Local changes in the bones of the skull are accompanied by the processes of osteolysis and osteogenesis and have uncertain dynamics.Changes in the state of bone tissue in cephalohematomas can be monitored b
Head and neck cancer represents a challenge for radiation oncologists due to accelerated repopulation of cancer cells during treatment.This study aims to simulate, using Monte Carlo methods, the response of a virtual head and neck tumor to both conventional and altered fractionation schedules in radiotherapy when accelerated repopulation is conside